Organofluorine Compounds

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Organofluorine Compounds

Organofluorine compounds exhibit outstanding chemical stability, hydrophobicity, and metabolic resistance due to strong C–F bonds. They are widely used in pharmaceuticals, agrochemicals, refrigerants, specialty polymers, and surface-modification agents. Their unique fluorine effects enhance bioavailability, thermal resistance, and material durability.

Fluoroaniline Series

The Fluoroaniline Series includes fluorinated aniline derivatives widely used as key intermediates in pharmaceutical synthesis, dyes, agricultural chemicals, and high-performance materials. The amino group significantly enhances reactivity, enabling participation in acylation, diazotization, reductive amination, and heterocycle formation. Fluoroanilines serve as starting materials for the synthesis of APIs, including anticancer agents, antiviral drugs, and neuroactive compounds. The presence of fluorine further improves lipophilicity, metabolic resistance, and biological potency. They are also important precursors in the synthesis of azo dyes, polyimide materials, and aromatic polyamides. Due to their strong electronic influence and broad functional utility, the Fluoroaniline Series remains indispensable in both industrial chemistry and advanced research applications.

4-Amino-3,5-Dichlorobenzotrifluoride CAS NO 24279-39-8

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CAS No.:24279-39-8

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3-Methyl-5-Trifluoromethylaniline CAS NO 96100-12-8

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CAS No.:96100-12-8

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2-Amino-5-Nitrobenzotrifluoride CAS NO 121-01-7

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CAS No.:121-01-7

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3-Amino-4-Chlorobenzotrifluoride CAS NO 121-50-6

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CAS No.:121-50-6

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3-Fluoro-Dl-Tyrosine CAS NO 139-26-4

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CAS No.:139-26-4

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4-Fluorobenzylamine CAS NO 140-75-0

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CAS No.:140-75-0

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5-Fluoro-Dl-Tryptophan CAS NO 154-08-5

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CAS No.:154-08-5

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2,4-Bis-(Trifluoromethyl)-Aniline CAS NO 167-71-5

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CAS No.:167-71-5

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Fluorophenylacetic Acid Series

The Fluorophenylacetic Acid Series includes a range of fluorinated phenylacetic acid derivatives widely used in pharmaceutical synthesis, agrochemicals, and fine chemicals. The introduction of fluorine enhances acidity, lipophilicity, and metabolic stability, enabling precise control of biological activity. These acids are key intermediates for producing amides, esters, and heterocycles used in antiviral drugs, anti-inflammatory agents, and CNS-active molecules. Their structural versatility supports applications in peptide synthesis, prodrug development, and chiral compound preparation. In industrial chemistry, fluorophenylacetic acids enable efficient formation of building blocks for liquid crystals, specialty polymers, and optical materials. Their electron-withdrawing nature also facilitates selective coupling and acylation reactions. Due to their stability and functionality, this series plays an essential role in the creation of advanced fluorinated molecular frameworks.

Difluoromethylthioacetic Acid Potassium Salt CAS NO 1797117-16-8

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CAS No.:1797117-16-8

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Fluoroacetic Acid CAS NO 144-49-0

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CAS No.:144-49-0

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Fluoroaceticacid CAS NO 144-49-1

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CAS No.:144-49-1

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2-Propenoic Acid, 3-(2-Fluorophenyl)-2-Methyl- CAS NO 1131-71-1

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CAS No.:1131-71-1

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L-4-Fluorophenylalanine CAS NO 1132-68-9

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CAS No.:1132-68-9

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3-[3-(Bis(2-Fluoroethyl)Amino)Phenyl]Propanoic Acid CAS NO 1148-78-3

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CAS No.:1148-78-3

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Ammonium 2,2,3,3-Tetrafluoropropionate CAS NO 1428-27-9

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CAS No.:1428-27-9

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2-Fluoro-3-Oxo-3-Phenylpropionic Acid Ethyl Ester CAS NO 1479-22-7

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CAS No.:1479-22-7

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Fluorophenol Series

The Fluorophenol Series comprises fluorinated phenols used as reactive intermediates in pharmaceuticals, agrochemicals, dyes, and polymer chemistry. The hydroxyl group combined with a fluorine substituent creates a highly tunable aromatic system with enhanced acidity, modified hydrogen bonding, and improved biological activity. Fluorophenols undergo etherification, esterification, coupling, and electrophilic substitution reactions, serving as precursors to aryl ethers, fluorinated polymers, and bioactive molecules. They are frequently incorporated into drug candidates due to their ability to influence metabolic stability and receptor affinity. Industrial applications include synthesis of antioxidants, UV absorbers, liquid crystal components, and advanced electronic materials. Fluorophenols provide a foundation for designing functional aromatic compounds with enhanced performance and reactivity.

4-(4-Fluorophenoxy)Phenol CAS NO 1524-19-2

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CAS No.:1524-19-2

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2-Fluoro-6-Nitrophenol CAS NO 1526-17-6

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CAS No.:1526-17-6

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4-Amino-2-(Trifluoromethyl)Phenol CAS NO 1535-76-8

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CAS No.:1535-76-8

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4-Nitro-2-Trifluoromethylphenol CAS NO 1548-61-4

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CAS No.:1548-61-4

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2-Nitro-6-(Trifluoromethyl)Phenol CAS NO 1548-62-5

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CAS No.:1548-62-5

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2-(4-Amino-3-Methoxyphenyl)-1,1,1,3,3,3-Hexafluoropropan-2-Ol CAS NO 1992-01-4

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CAS No.:1992-01-4

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2-(4-Amino-3-Methylphenyl)Hexafluoroisopropanol CAS NO 1992-09-2

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CAS No.:1992-09-2

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Tetrafluorobenzene-1,2-Diol CAS NO 1996-23-2

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CAS No.:1996-23-2

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Fluorophenylboronic Acid Series

The Fluorophenylboronic Acid Series includes boronic acids containing fluorinated aromatic rings, widely used in Suzuki–Miyaura cross-coupling and other metal-catalyzed transformations. These compounds serve as essential partners for constructing biaryl structures, heterocycles, and functional molecules found in pharmaceuticals, OLED materials, and fine chemicals. Fluorination enhances stability, modulates electron density, and improves binding properties, making these boronic acids valuable in medicinal chemistry and materials science. Their predictable reactivity allows precise synthesis of fluorinated aromatic frameworks with high yield and selectivity. Industrial applications include liquid crystal intermediates, agrochemical actives, and catalysts. The Fluorophenylboronic Acid Series remains a crucial toolkit for building complex fluorinated molecular architectures.

2-Fluorophenylboronic Acid CAS NO 1193-03-9

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CAS No.:1193-03-9

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3-(Trifluoromethyl)Phenylboronic Acid CAS NO 1423-26-3

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CAS No.:1423-26-3

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3-(Trifluoromethyl)Phenylboronicacid CAS NO 1423-26-6

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CAS No.:1423-26-6

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2-Trifluoromethylphenylboronic Acid CAS NO 1423-27-4

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CAS No.:1423-27-4

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2,3,4,5,6-Pentafluorobenzeneboronic Acid CAS NO 1582-24-7

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CAS No.:1582-24-7

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4-Chlorophenylboronic Acid CAS NO 1679-18-1

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CAS No.:1679-18-1

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2-Fluoro-5-(Trifluoromethyl)Benzenesulphonyl Chloride CAS NO 1744-43-0

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CAS No.:1744-43-0

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4-Fluorobenzeneboronic Acid CAS NO 1765-93-1

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CAS No.:1765-93-1

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Fluoronitrobenzene Series

The Fluoronitrobenzene Series consists of fluorinated nitrobenzene derivatives widely used as key intermediates in pharmaceuticals, agrochemicals, dyes, and advanced materials. The combination of fluorine and a nitro substituent produces highly activated aromatic systems suitable for nucleophilic aromatic substitution, reduction, and heterocycle formation. These compounds serve as precursors to fluoroanilines, fluorophenols, and aminated heterocycles found in modern drug molecules. Their strong electron-withdrawing effects enhance reactivity and enable controlled introduction of functional groups at specific positions on the aromatic ring. Industrial applications include synthesis of antibacterial agents, herbicides, high-performance pigments, and electronic materials. Fluoronitrobenzenes remain indispensable for constructing complex fluorinated aromatic frameworks with precise electronic tuning.

5-Chloro-2-Nitrobenzotrifluoride CAS NO 118-83-2

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CAS No.:118-83-2

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4-Chloro-3-Nitrobenzotrifluoride CAS NO 121-17-5

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CAS No.:121-17-5

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