Description

4-Amino-2,6-Difluorophenol is a versatile fluorinated aromatic amine-phenol hybrid compound, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino and a hydroxyl group on a difluorinated benzene ring, makes it a valuable precursor for creating complex molecules with tailored properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, improving electronic properties and device performance.
• Polymer & Resin Modifier: Incorporated as a monomer or cross-linking agent to produce high-performance polymers with enhanced thermal stability, chemical resistance, and specific optical characteristics.
• Dye & Pigment Manufacturing: Acts as a precursor for synthesizing specialized fluorinated dyes and pigments used in inks, coatings, and imaging technologies.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination chemistry, coupling reactions, and material science applications.

Basic Information

Product Name	4-Amino-2,6-Difluorophenol
CAS No.	126058-97-7
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	2,6-Difluoro-4-aminophenol; 4-Amino-2,6-difluorophenol; 2,6-Difluoro-4-hydroxyaniline; 4-Hydroxy-2,6-difluoroaniline; Phenol, 4-amino-2,6-difluoro-; 4-Amino-2,6-difluorophenol (A2DFP); 126058-97-7; 2,6-Difluoro-4-aminophenol
EINECS	Contact for details

Quality Control

Our 4-Amino-2,6-Difluorophenol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.