Description

Boronic Acid, B-[4-[3-(Trifluoromethyl)Phenoxy]Phenyl]- is a specialized aromatic boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex biaryl motifs for oncology, CNS, and antiviral therapies.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the trifluoromethylphenoxy group for enhanced biological activity and stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: A premier reagent for palladium-catalyzed carbon-carbon bond formation, prized for its stability and reactivity profile in constructing sterically demanding biaryl systems.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and sensors for studying biological processes, capitalizing on boronic acid's affinity for diols.
• Catalyst & Ligand Preparation: Acts as a starting material for synthesizing novel organoboron ligands and catalysts used in asymmetric synthesis.

Basic Information

Product Name	Boronic Acid, B-[4-[3-(Trifluoromethyl)Phenoxy]Phenyl]-
CAS No.	958457-42-6
Molecular Formula	C13H10BF3O3
Molecular Weight	282.03 g/mol
Synonyms	[4-(3-Trifluoromethylphenoxy)phenyl]boronic acid; 4-[3-(Trifluoromethyl)phenoxy]benzeneboronic acid; B-[4-[3-(Trifluoromethyl)phenoxy]phenyl]boronic acid; (4-(3-(Trifluoromethyl)phenoxy)phenyl)boronic acid; 4-(3-Trifluoromethylphenoxy)phenylboronic acid; 958457-42-6; Boronic acid, B-[4-[3-(trifluoromethyl)phenoxy]phenyl]-
EINECS	Contact for details

Quality Control

Our production of Boronic Acid, B-[4-[3-(Trifluoromethyl)Phenoxy]Phenyl]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and elemental analysis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support cGMP manufacturing standards for pharmaceutical customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (argon or nitrogen) for long-term storage to prevent degradation. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (HPLC)	≥98.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.