Description

2-(4-Amino-3-Methoxyphenyl)-1,1,1,3,3,3-Hexafluoropropan-2-Ol is a high-value fluorinated aromatic building block characterized by its unique combination of an amino group, a methoxy substituent, and a hexafluoroisopropanol moiety. This compound is essential for advanced synthesis, offering a versatile scaffold for constructing complex molecules with tailored properties. It is primarily sought by R&D chemists and process developers in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry and specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing compounds used in electronic displays and organic light-emitting diodes due to its impact on electronic properties and stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart unique characteristics such as enhanced chemical resistance, thermal stability, or specific surface properties.
• Complex Ligand & Catalyst Development: Utilized in organometallic chemistry to create sophisticated ligands for asymmetric catalysis and other advanced synthetic methodologies.
• Research & Development: A valuable tool for academic and industrial research in exploring new chemical spaces and reaction pathways involving fluorinated aromatics.

Basic Information

Product Name	2-(4-Amino-3-Methoxyphenyl)-1,1,1,3,3,3-Hexafluoropropan-2-Ol
CAS No.	1992-01-4
Molecular Formula	C10H9F6NO2
Molecular Weight	289.17 g/mol
Synonyms	2-(4-Amino-3-methoxyphenyl)hexafluoroisopropanol; 4-Amino-3-methoxy-α,α-bis(trifluoromethyl)benzenemethanol; 1,1,1,3,3,3-Hexafluoro-2-(4-amino-3-methoxyphenyl)propan-2-ol; 2-(4-Amino-3-methoxyphenyl)-1,1,1,3,3,3-hexafluoro-2-propanol; Hexafluoro-2-(4-amino-3-methoxyphenyl)isopropanol; 4-Amino-3-methoxy-α-(trifluoromethyl)benzenemethanol (related); HFIP-Amino Anisole Derivative
EINECS	Contact for details

Quality Control

Our production of 2-(4-Amino-3-Methoxyphenyl)-1,1,1,3,3,3-Hexafluoropropan-2-Ol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting customer specifications. Certificates of Analysis (COA) documenting all critical parameters are provided and can be tailored to support regulatory filings in pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.