Description

4-Difluoromethoxy-2-Nitro-Aniline is a specialized aromatic amine derivative featuring both difluoromethoxy and nitro functional groups. This compound serves as a critical high-purity intermediate for the synthesis of advanced molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily required by R&D chemists and process development scientists for constructing complex heterocycles and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in therapeutic areas requiring fluorinated compounds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoromethoxy group can improve biological activity and environmental profile.
• Dye and Pigment Precursor: Serves as an intermediate in the manufacture of specialized azo dyes and pigments, leveraging the nitro and amine groups for color development.
• Material Science Research: Employed in the development of advanced polymers and functional materials, where its unique structure can impart specific electronic or surface properties.
• Organic Synthesis Reagent: A versatile reagent in academic and industrial laboratories for introducing the difluoromethoxy-aniline moiety into more complex molecular architectures.

Basic Information

Product Name	4-Difluoromethoxy-2-Nitro-Aniline
CAS No.	97963-76-3
Molecular Formula	C7H6F2N2O3
Molecular Weight	204.13 g/mol
Synonyms	2-Nitro-4-(difluoromethoxy)aniline; 4-(Difluoromethoxy)-2-nitrobenzenamine; 2-Nitro-4-difluoromethoxyaniline; Benzenamine, 4-(difluoromethoxy)-2-nitro-; 97963-76-3; 4-Difluoromethoxy-2-nitroaniline; 2-Nitro-4-difluoromethoxy aniline
EINECS	Contact for details

Quality Control

Every batch of 4-Difluoromethoxy-2-Nitro-Aniline is produced under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.