Description

3-Fluoro-2-(Methylthiomethoxy)Phenylboronic Acid is a specialized organoboron building block of significant interest in modern synthetic chemistry. Its value lies in its dual functional groups, enabling its use as a key intermediate in the construction of complex molecular architectures via cross-coupling reactions. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials. The CAS number for this compound is provided in the table below.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the introduction of the fluorine atom can enhance biological activity and stability.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences sector with tailored, high-value intermediates.

Basic Information

Product Name	3-Fluoro-2-(Methylthiomethoxy)Phenylboronic Acid
CAS No.	958454-11-0
Molecular Formula	C8H10BFO3S
Molecular Weight	216.04 g/mol
Synonyms	[2-(Methylsulfanylmethoxy)-3-fluorophenyl]boronic acid; (3-Fluoro-2-((methylthio)methoxy)phenyl)boronic acid; 3-Fluoro-2-((methylthio)methoxy)benzeneboronic acid; 2-(Methylthiomethoxy)-3-fluorobenzeneboronic acid; Boronic acid, B-[3-fluoro-2-[(methylthio)methoxy]phenyl]-; 958454-11-0
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-(Methylthiomethoxy)Phenylboronic Acid is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.