Description

2-Fluoro-4-Trimethylsilylaniline is a specialized organosilicon building block featuring both an aromatic amine and a silyl-protecting group. This compound matters for its dual functionality, enabling its use as a key intermediate in the synthesis of complex molecules where precise structural control is required. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing novel drug candidates and functional polymers.

Application

• Pharmaceutical intermediate for the synthesis of fluorinated active pharmaceutical ingredients (APIs).
• Building block in medicinal chemistry for creating compound libraries and exploring structure-activity relationships (SAR).
• Precursor for advanced materials, including liquid crystals and organic semiconductors.
• Intermediate in agrochemical research for developing new crop protection agents.
• Reagent in organic synthesis for introducing the 2-fluoro-4-(trimethylsilyl)aniline moiety into target molecules.
• Starting material for the preparation of ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	2-Fluoro-4-Trimethylsilylaniline
CAS No.	955372-99-3
Molecular Formula	C9H14FNSi
Molecular Weight	183.30 g/mol
Synonyms	4-(Trimethylsilyl)-2-fluoroaniline; 2-Fluoro-4-(trimethylsilyl)benzenamine; 2-Fluoro-4-(trimethylsilyl)phenylamine; Benzenamine, 2-fluoro-4-(trimethylsilyl)-; 2-Fluoro-4-trimethylsilylaniline; 2-Fluoro-4-TMS-aniline; 4-Amino-3-fluorophenyltrimethylsilane
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Trimethylsilylaniline undergoes rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data, including HPLC purity, NMR, and MS confirmation. Certificates of Analysis (COA) are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.