Description

2-Chloro-6-Hydroxyphenylboronic Acid is a versatile boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, where the boronic acid group enables efficient cross-coupling reactions, and the chloro and hydroxyl substituents provide handles for further chemical elaboration. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules and developing active ingredients through Suzuki-Miyaura coupling.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its structural motifs.
• Material Science Research: Employed in the creation of organic electronic materials, polymers, and ligands for catalysis due to its functional handles.
• Chemical Biology & Proteomics: Acts as a building block for synthesizing molecular probes, inhibitors, and tools for studying biological processes.
• Academic & R&D Laboratories: Serves as a fundamental reagent for methodological development in organic synthesis and catalysis research.
• Ligand Synthesis for Catalysis: Utilized to prepare sophisticated bidentate or tridentate ligands for transition metal catalysts.

Basic Information

Product Name	2-Chloro-6-Hydroxyphenylboronic Acid
CAS No.	958646-70-3
Molecular Formula	C6H6BClO3
Molecular Weight	172.37 g/mol
Synonyms	(2-Chloro-6-hydroxyphenyl)boronic acid; 2-Chloro-6-hydroxybenzeneboronic acid; B-(2-Chloro-6-hydroxyphenyl)boronic acid; 958646-70-3; Boronic acid, B-(2-chloro-6-hydroxyphenyl)-; 2-Chloro-6-hydroxy-phenylboronic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Hydroxyphenylboronic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.