Description

2-Fluoro-5-(Methylthiomethoxy)Phenylboronic Acid is a specialized organoboron compound that serves as a crucial building block in modern synthetic chemistry. Its value lies in its dual functional groups, enabling it to act as a versatile coupling partner in cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This high-purity intermediate is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those requiring complex biaryl or heterobiaryl structures.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products, such as herbicides and fungicides.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in catalytic systems.
• Material Science Research: Employed in the development of organic electronic materials, including OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the construction of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical reagent for CROs and CDMOs engaged in custom synthesis projects for clients.

Basic Information

Product Name	2-Fluoro-5-(Methylthiomethoxy)Phenylboronic Acid
CAS No.	958454-12-1
Molecular Formula	C8H10BFO3S
Molecular Weight	216.04 g/mol
Synonyms	[2-Fluoro-5-(methylsulfanylmethoxy)phenyl]boronic acid; (2-Fluoro-5-((methylthio)methoxy)phenyl)boronic acid; 2-Fluoro-5-[(methylthio)methoxy]benzeneboronic acid; 5-(Methylthiomethoxy)-2-fluorophenylboronic acid; B-[2-Fluoro-5-(methylthiomethoxy)phenyl]boronic acid; CAS 958454-12-1
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Methylthiomethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected in GMP-like environments for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.