Description

1-[4-(2,2,2-Trifluoroethoxy)Phenyl]Ethan-1-Amine is a high-purity, specialized aromatic amine derivative featuring a trifluoroethoxy substituent. This compound matters as a critical building block in advanced organic synthesis, offering a unique combination of aromaticity and fluorine chemistry for creating novel molecular architectures. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the trifluoroethoxy group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands or catalysts used in asymmetric synthesis and other specialized organic transformations.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, or organic electronic materials requiring fluorine-containing aromatic amines.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags, affinity labels, or other molecular probes in biochemical research.

Basic Information

Product Name	1-[4-(2,2,2-Trifluoroethoxy)Phenyl]Ethan-1-Amine
CAS No.	942938-39-8
Molecular Formula	C10H12F3NO
Molecular Weight	219.20 g/mol
Synonyms	1-[4-(2,2,2-Trifluoroethoxy)phenyl]ethanamine; 4-(2,2,2-Trifluoroethoxy)phenethylamine; 1-(4-(2,2,2-Trifluoroethoxy)phenyl)ethan-1-amine; α-Methyl-4-(2,2,2-trifluoroethoxy)benzeneethanamine; 2-[4-(2,2,2-Trifluoroethoxy)phenyl]ethanamine (common mis-assignment); p-(2,2,2-Trifluoroethoxy)phenethylamine; 4-(Trifluoroethoxy)benzeneethanamine, α-methyl-
EINECS	Contact for details

Quality Control

Our 1-[4-(2,2,2-Trifluoroethoxy)Phenyl]Ethan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.