Description

3-(1H-Imidazol-1-Yl)-5-(Trifluoromethyl)Aniline is a high-value, multi-functional aromatic amine building block featuring both an imidazole and a trifluoromethyl group. This unique molecular structure makes it a critical intermediate for the synthesis of advanced pharmaceuticals and agrochemicals, where it imparts desirable biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in oncology, antiviral, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the imidazole and trifluoromethyl motifs.
• Ligand and Catalyst Preparation: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of advanced polymers and functional organic materials with specific electronic or binding properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems and enzyme inhibition.

Basic Information

Product Name	3-(1H-Imidazol-1-Yl)-5-(Trifluoromethyl)Aniline
CAS No.	943320-48-7
Molecular Formula	C10H8F3N3
Molecular Weight	227.19 g/mol
Synonyms	5-(Trifluoromethyl)-3-(1H-imidazol-1-yl)aniline; 3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)benzenamine; 1-[3-Amino-5-(trifluoromethyl)phenyl]-1H-imidazole; 3-Imidazol-1-yl-5-trifluoromethylaniline; Benzenamine, 3-(1H-imidazol-1-yl)-5-(trifluoromethyl)-; 3-Amino-5-(trifluoromethyl)phenylimidazole
EINECS	Contact for details

Quality Control

Our production of 3-(1H-Imidazol-1-Yl)-5-(Trifluoromethyl)Aniline adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.