Description

2-Bromo-4-(Pentafluorosulphanyl)Phenol, also known as 2-Bromo-4-(Pentafluorothio)Phenol, is a high-value fluorinated phenolic intermediate with a unique pentafluorosulfanyl (SF5) functional group. This compound is critical for introducing the highly electronegative, lipophilic, and thermally stable SF5 moiety into advanced molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its properties can significantly influence bioavailability and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the SF5 group enhances lipophilicity and biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent for creating specialty polymers and advanced materials with unique surface properties and chemical resistance.
• Liquid Crystal & OLED Chemistry: Employed in the synthesis of fluorinated components for electronic display materials, leveraging its electronic and steric characteristics.
• Organic Synthesis & Catalysis: A versatile reagent for constructing complex aromatic systems in academic and industrial research laboratories.
• Chemical Biology Probes: Useful for tagging and modifying biomolecules in proteomics and diagnostic assay development due to its distinct spectroscopic signature.

Basic Information

Product Name	2-Bromo-4-(Pentafluorosulphanyl)Phenol, 2-Bromo-4-(Pentafluorothio)Phenol
CAS No.	1426290-12-1
Molecular Formula	C6H2BrF5OS
Molecular Weight	293.04 g/mol
Synonyms	2-Bromo-4-(pentafluoro-λ⁶-sulfanyl)phenol; 4-SF5-2-Bromophenol; Phenol, 2-bromo-4-(pentafluorothio)-; 2-Bromo-4-pentafluorosulfanylphenol; 2-Br-4-SF5-PhOH; 2-Bromo-4-(SF5)phenol; 2-Bromo-4-(pentafluorosulfuranyl)phenol
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-(Pentafluorosulphanyl)Phenol is manufactured and analyzed under strict quality management protocols to ensure consistency and purity for sensitive R&D and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali. Keep away from incompatible materials and moisture. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.