Description

4-Fluoro-2-(Methylthiomethoxy)Phenylboronic Acid is a specialized organoboron compound that serves as a crucial building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing complex fluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific fluorinated aromatic structures.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular architecture is critical.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the life sciences sector.

Basic Information

Item	Detail
Product Name	4-Fluoro-2-(Methylthiomethoxy)Phenylboronic Acid
CAS No.	958454-10-9
Molecular Formula	C9H12BFO3S
Molecular Weight	230.06 g/mol
Synonyms	[4-Fluoro-2-(methylsulfanylmethoxy)phenyl]boronic acid; (4-Fluoro-2-((methylthio)methoxy)phenyl)boronic acid; 2-(Methylthiomethoxy)-4-fluorophenylboronic acid; 4-Fluoro-2-(methylthiomethoxy)benzeneboronic acid; Boronic acid, B-[4-fluoro-2-[(methylthio)methoxy]phenyl]-; CAS 958454-10-9
EINECS	Contact for details

Quality Control

Every batch of our 4-Fluoro-2-(Methylthiomethoxy)Phenylboronic Acid is produced under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.