Description

2-Bromo-4-(Trifluoromethoxy)Phenylboronic Acid is a specialized organoboron compound that serves as a crucial synthetic intermediate in modern organic chemistry. Its value lies in its ability to participate in key cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This high-purity building block is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing trifluoromethoxy and bromo substituents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the unique properties of the trifluoromethoxy group can enhance biological activity.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where precise molecular structure is critical.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical suppliers and CROs/CMOs offering bespoke synthesis services to global clients.

Basic Information

Product Name	2-Bromo-4-(Trifluoromethoxy)Phenylboronic Acid
CAS No.	959997-86-5
Molecular Formula	C7H5BBrF3O3
Molecular Weight	284.83 g/mol
Synonyms	[2-Bromo-4-(trifluoromethoxy)phenyl]boronic acid; (2-Bromo-4-trifluoromethoxyphenyl)boronic acid; 2-Bromo-4-(trifluoromethoxy)benzeneboronic acid; B-[2-Bromo-4-(trifluoromethoxy)phenyl]boronic acid; 959997-86-5; Boronic acid, B-[2-bromo-4-(trifluoromethoxy)phenyl]-; 2-Bromo-4-trifluoromethoxy phenylboronic acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(Trifluoromethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.