Description

2-(4'-Bromo-[1,1'-Biphenyl]-4-Yl)-2,2-Difluoroacetic Acid is a high-value, multi-functional organic building block characterized by its biphenyl core and difluoroacetic acid moiety. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), enabling precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and liquid crystal display (LCD) industries for developing novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and kinase inhibitors.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the biphenyl structure contributes to biological activity.
• Liquid Crystal Materials: Serves as a precursor for the synthesis of fluorinated liquid crystal compounds used in high-performance displays.
• Organic Light-Emitting Diodes (OLEDs): Employed in the creation of electron-transport or host materials for OLED devices due to its aromatic and fluorinated structure.
• Material Science Research: Acts as a versatile building block for creating novel polymers and small molecules with specific electronic or optical properties.
• Cross-Coupling Reactions: The bromine substituent makes it a valuable substrate for palladium-catalyzed reactions like Suzuki-Miyaura coupling to construct complex biaryl systems.

Basic Information

Product Name	2-(4'-Bromo-[1,1'-Biphenyl]-4-Yl)-2,2-Difluoroacetic Acid
CAS No.	1436389-34-2
Molecular Formula	C14H9BrF2O2
Molecular Weight	327.12 g/mol
Synonyms	2-(4'-Bromobiphenyl-4-yl)-2,2-difluoroacetic Acid; 4'-Bromo-4-(difluorocarboxymethyl)biphenyl; [1,1'-Biphenyl]-4-acetic acid, 4'-bromo-α,α-difluoro-; 2,2-Difluoro-2-(4'-bromo[1,1'-biphenyl]-4-yl)acetic Acid; α,α-Difluoro-4'-(bromo)[1,1'-biphenyl]-4-acetic Acid; 1436389-34-2; 2-(4'-Bromo-[1,1'-biphenyl]-4-yl)-2,2-difluoroethanoic Acid
EINECS	Contact for details

Quality Control

Our 2-(4'-Bromo-[1,1'-Biphenyl]-4-Yl)-2,2-Difluoroacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive and should be handled under inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.