Description

2,3,5,6-Tetrafluorophenol is a highly fluorinated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring four fluorine atoms on the aromatic ring, imparts significant electron-withdrawing properties and enhanced stability, making it a valuable intermediate for demanding applications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors who require precise fluorination to modify the properties of target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs requiring fluorinated aromatic systems to improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where fluorination enhances activity and environmental persistence.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystals used in high-performance displays due to its ability to influence dielectric anisotropy and viscosity.
• Polymer & Resin Modifier: Incorporated into specialty polymers and epoxy resins to improve chemical resistance, thermal stability, and surface properties.
• Organic Electronics: Utilized in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors, where fluorine substitution tunes electronic energy levels.
• Chemical Research & Development: A versatile reagent for exploring new fluorination chemistry and creating novel fluorinated compounds in academic and industrial R&D labs.

Basic Information

Product Name	2,3,5,6-Tetrafluorophenol
CAS No.	769-39-1
Molecular Formula	C6H2F4O
Molecular Weight	166.07 g/mol
Synonyms	2,3,5,6-Tetrafluorophenol; Perfluorophenol (ambiguous, but used); 2,3,5,6-Tetrafluoro-1-hydroxybenzene; Phenol, 2,3,5,6-tetrafluoro-; TFP; NSC 88456; Tetrafluorophenol
EINECS	212-216-5

Quality Control

Our 2,3,5,6-Tetrafluorophenol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	95 - 99 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.