Description

2-Fluoro-4-Methyl-Dl-Phenylglycine is a fluorinated phenylglycine derivative, a key chiral building block in advanced organic synthesis. Its value lies in the strategic incorporation of fluorine and methyl groups, which can significantly alter the physicochemical and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine atom enhances bioavailability and environmental stability.
• Peptidomimetics & Bioactive Molecule Design: Serves as a non-natural amino acid analog for constructing peptide-like molecules with improved metabolic stability and binding affinity.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Research: A valuable probe for studying enzyme mechanisms and protein-ligand interactions due to its fluorine label and structural mimicry.
• Material Science Precursor: Potential starting material for specialty polymers and advanced organic materials with tailored electronic properties.

Basic Information

Product Name	2-Fluoro-4-Methyl-Dl-Phenylglycine
CAS No.	1039118-67-6
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	DL-2-Fluoro-4-methylphenylglycine; (±)-2-Amino-2-(2-fluoro-4-methylphenyl)acetic acid; 2-Fluoro-4-methyl-DL-α-phenylglycine; 2-Fluoro-4-methyl-DL-α-aminophenylacetic acid; (RS)-2-Amino-2-(2-fluoro-4-methylphenyl)ethanoic acid; 2-Fluoro-4-methyl-DL-homophenylglycine; FMPG; 2-F-4-Me-DL-Phg
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Methyl-Dl-Phenylglycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets exacting research and development standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-Ratio ~50:50
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.