Description

1-Ethyl-2-Fluoro-4-Methoxy-5-Nitrobenzene is a high-purity fluorinated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for developing active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating fluorinated aromatic cores in electronic and photonic materials.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized, light-fast dyes and pigments for high-performance applications.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Chemical Research & Development: Utilized in academic and industrial R&D settings for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	1-Ethyl-2-Fluoro-4-Methoxy-5-Nitrobenzene
CAS No.	1089282-52-9
Molecular Formula	C9H10FNO3
Molecular Weight	199.18 g/mol
Synonyms	2-Fluoro-4-methoxy-5-nitroethylbenzene; 1-Ethyl-2-fluoro-4-methoxy-5-nitrobenzene; 5-Nitro-2-fluoro-4-methoxyethylbenzene; Benzene, 1-ethyl-2-fluoro-4-methoxy-5-nitro-; 4-Methoxy-5-nitro-2-fluoroethylbenzene
EINECS	Contact for details

Quality Control

Our 1-Ethyl-2-Fluoro-4-Methoxy-5-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.