Description

6-Amino-2,3-difluorophenol is a versatile fluorinated aromatic amine-phenol derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amine and a phenol group on a difluorinated benzene ring, makes it a high-value intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluorophenol moiety enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs) due to its ability to modify electronic properties and stability.
• Polymer & Resin Modifier: Incorporated as a monomer or cross-linking agent to impart specific properties like chemical resistance, thermal stability, or adhesion in high-performance polymers.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments for high-value applications.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination chemistry and creating compound libraries for screening.

Basic Information

Item	Detail
Product Name	6-Amino-2,3-difluorophenol
CAS No.	115551-33-2
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	2,3-Difluoro-6-aminophenol; 2-Amino-3,4-difluorophenol; 3,4-Difluoro-2-aminophenol; 6-Amino-2,3-difluorophenol; 2,3-Difluoro-6-hydroxyaniline; 2,3-Difluoro-6-aminophenol; 3,4-Difluoro-2-hydroxyaniline; 6-Amino-2,3-difluoro-1-hydroxybenzene
EINECS	Contact for details

Quality Control

Our 6-Amino-2,3-difluorophenol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.