Description

Ethyl 2,2-Difluoro-2-Mesitylacetate is a specialized fluorinated building block of significant interest in advanced organic synthesis. This compound matters for its unique structural motif, combining a mesityl group with a difluoroacetate ester, which is valuable for introducing fluorinated moieties into complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic or heterocyclic structures to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides where the difluoroacetate group can enhance biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized fluorinated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of fluorinated polymers and advanced organic electronic materials to alter solubility and electronic properties.
• Fluorine Chemistry Research: An essential reagent for academic and industrial research focused on new methodologies for C-F bond formation and functionalization.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing high-value, fluorinated specialty chemicals.

Basic Information

Item	Details
Product Name	Ethyl 2,2-Difluoro-2-Mesitylacetate
CAS No.	1436389-43-3
Molecular Formula	C₁₃H₁₆F₂O₂
Molecular Weight	242.26 g/mol
Synonyms	2,2-Difluoro-2-mesitylacetic Acid Ethyl Ester; Ethyl 2,2-Difluoro-2-(2,4,6-trimethylphenyl)acetate; 2-Mesityl-2,2-difluoroacetic Acid Ethyl Ester; α,α-Difluoro-2,4,6-trimethylbenzeneacetic Acid Ethyl Ester; Ethyl α,α-Difluoro-2,4,6-trimethylphenylacetate; Difluoro(mesityl)acetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 2,2-Difluoro-2-Mesitylacetate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specification parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.