Description

2-Bromo-5-Fluorobenzeneboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to introduce functionalized aromatic fragments into target structures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl or heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific halogenated aromatic motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the construction of organic electronic materials, such as those for OLEDs and organic semiconductors, where precise molecular architecture is critical.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CROs/CMOs serving the life sciences industry.

Basic Information

Product Name	2-Bromo-5-Fluorobenzeneboronic Acid
CAS No.	959996-48-6
Molecular Formula	C6H5BBrFO2
Molecular Weight	218.82 g/mol
Synonyms	(2-Bromo-5-fluorophenyl)boronic acid; 2-Bromo-5-fluorophenylboronic acid; B-(2-Bromo-5-fluorophenyl)boronic acid; 959996-48-6; Boronic acid, B-(2-bromo-5-fluorophenyl)-; 2-Bromo-5-fluoro-benzeneboronic acid; 5-Fluoro-2-bromobenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluorobenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.