Description

2-Chloro-6-Fluoro-5-Hydroxyphenylboronic Acid is a high-purity boronic acid derivative serving as a critical building block in modern synthetic chemistry. This compound is valued for its unique halogenated and hydroxylated phenyl structure, which enables precise cross-coupling reactions essential for constructing complex molecules. It is primarily required by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and pesticides with tailored biological activity.
• Material Science: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and organic electronic materials.
• Chemical Synthesis: Employed as a versatile building block for creating complex, multi-functional aromatic compounds in organic chemistry.
• Ligand Synthesis: Useful for preparing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Life Sciences Research: Utilized in biochemical probe and diagnostic reagent development due to its specific reactive handle.

Basic Information

Product Name	2-Chloro-6-Fluoro-5-Hydroxyphenylboronic Acid
CAS No.	958646-67-8
Molecular Formula	C6H5BClFO3
Molecular Weight	189.37 g/mol
Synonyms	(2-Chloro-6-fluoro-5-hydroxyphenyl)boronic acid; 5-Borono-3-chloro-2-fluorophenol; 2-Fluoro-6-hydroxy-3-chlorophenylboronic acid; Boronic acid, B-(2-chloro-6-fluoro-5-hydroxyphenyl)-; 958646-67-8; 2-Chloro-6-fluoro-5-hydroxybenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Fluoro-5-Hydroxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.