Description

Zolmitriptan CAS NO 868622-23-5 is a potent and selective serotonin (5-HT1B/1D) receptor agonist belonging to the triptan class of pharmaceuticals. This compound is critical for the effective treatment of acute migraine headaches, offering significant relief from pain and associated symptoms. It is an essential active pharmaceutical ingredient (API) for pharmaceutical manufacturers developing migraine-specific therapeutics. Our supply ensures high purity and consistent quality, meeting the stringent demands of global pharmaceutical production.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of migraine relief medications.
• Tablet Manufacturing: Used in the production of conventional oral tablets for migraine treatment.
• Orally Disintegrating Tablet (ODT) Formulation: Suitable for fast-dissolving dosage forms that provide rapid onset of action.
• Nasal Spray Formulation: Incorporated into intranasal delivery systems for patients requiring non-oral administration.
• Generic Drug Production: Serves as a key raw material for manufacturers of generic zolmitriptan products.
• Clinical Research & Development: Utilized in preclinical and clinical studies for new migraine therapies.
• Reference Standard: High-purity grades are applicable for use as analytical reference standards in quality control laboratories.

Basic Information

Product Name	Zolmitriptan
CAS No.	868622-23-5
Molecular Formula	C16H21N3O2
Molecular Weight	287.36 g/mol
Synonyms	(S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone; Zolmitriptan; Zomig; 311C90; Zolmitriptanum; Zolmitriptano; Zolmitriptanum [INN-Latin]
EINECS	Contact for details

Quality Control

Our Zolmitriptan is manufactured under strict quality management systems to ensure it meets the highest standards for pharmaceutical use. Each batch is tested against rigorous specifications, including identity, purity, and impurity profiles, utilizing advanced analytical techniques such as HPLC and NMR. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all test results. We can supply material compliant with various pharmacopoeial standards, including USP and EP, upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.