Description

Zolmitriptan is a potent and selective serotonin (5-HT1B/1D) receptor agonist. This compound is a critical active pharmaceutical ingredient (API) primarily used in the treatment of acute migraine and cluster headaches. It is essential for pharmaceutical manufacturers developing fast-acting and effective migraine therapies. Global demand is driven by its proven efficacy in providing rapid relief from migraine symptoms with minimal side effects.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription migraine medications (tablets, orally disintegrating tablets, nasal sprays).
• Generic Drug Manufacturing: Sourcing for the production of bioequivalent generic versions of branded Zolmitriptan products.
• Clinical Research: Utilization as a reference standard or raw material in pharmacokinetic and pharmacodynamic studies.
• Formulation Development: Serves as the key component in R&D for novel drug delivery systems aimed at improving bioavailability and patient compliance.
• Contract Manufacturing: Supply to CDMOs (Contract Development and Manufacturing Organizations) for full-scale commercial production.

Basic Information

Product Name	Zolmitriptan
CAS No.	139264-24-7
Molecular Formula	C16H21N3O2
Molecular Weight	287.36 g/mol
Synonyms	(S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone; Zomig; 311C90; Zolmitriptanum; Zolmitriptano; Zolmitriptanum [INN-Latin]; Zolmitriptan [USAN:INN]; (4S)-4-({3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
EINECS	Contact for details

Quality Control

Our Zolmitriptan is manufactured under strict quality management systems. We ensure compliance with major pharmacopoeial standards, including ICH Q7 guidelines for active pharmaceutical ingredients. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our rigorous quality testing protocols include validated analytical methods (HPLC, GC, NMR) to guarantee batch-to-batch consistency and regulatory compliance for global markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water Content (KF)	NMT 0.5%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm
Related Substances (HPLC)	Total impurities NMT 1.0% Any individual impurity NMT 0.5%
Optical Rotation	Specific range provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.