Description

Cinanserin Hydrochloride is a selective serotonin receptor antagonist of significant interest in pharmaceutical research and development. This compound is a crucial intermediate and reference standard for investigating neurological pathways and developing novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in neuroscience and CNS drug discovery.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in drug substance and product testing.
• Neuroscience Research: Acts as a key pharmacological tool for studying serotonin (5-HT) receptor subtypes, particularly 5-HT2A and 5-HT2C, in preclinical models.
• Drug Discovery Intermediate: Serves as a critical building block or precursor in the synthetic pathway for new chemical entities targeting serotonin-related disorders.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) and in vitro assays to identify and characterize new receptor ligands.
• Academic Research: Utilized in university and institutional labs for fundamental studies on serotonin's role in behavior, mood, and perception.

Basic Information

Product Name	Cinanserin Hydrochloride
CAS No.	1166-34-3
Molecular Formula	C20H23N3O2S • HCl
Molecular Weight	405.94 g/mol
Synonyms	SQ 10,643; 2'-[3-(Dimethylamino)propyl]thio]cinnamanilide Hydrochloride; Cinanserin HCl; 1-Cinnamoyl-2-[(3-dimethylaminopropyl)thio]phenylamine Hydrochloride; N-[2-[[3-(Dimethylamino)propyl]thio]phenyl]cinnamamide Hydrochloride
EINECS	Contact for details

Quality Control

Our Cinanserin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets stringent specifications for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.