Description

Eletriptan CAS NO 143322-58-1 is a potent and selective serotonin (5-HT1B/1D) receptor agonist, belonging to the triptan class of pharmaceuticals. It is a critical active pharmaceutical ingredient (API) specifically developed for the acute treatment of migraine headaches with or without aura. This compound matters for its efficacy in providing rapid relief from migraine symptoms by inducing cranial vasoconstriction and inhibiting neurogenic inflammation. Pharmaceutical manufacturers and research institutions require high-purity Eletriptan for the formulation of finished dosage forms and for ongoing neurological research.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of prescription migraine medications (e.g., tablets).
• Neurological Research: Used as a reference standard and investigational compound in studies targeting serotonin receptors and migraine pathophysiology.
• Formulation Development: Serves as a key component in the R&D of new drug delivery systems, such as orally disintegrating tablets or fast-dissolving formulations.
• Generic Drug Production: Essential for companies developing bioequivalent versions of branded Eletriptan hydrobromide products.
• Analytical Standard: Employed in quality control laboratories for HPLC, LC-MS, or spectroscopic method development and validation.
• Clinical Trial Material (CTM): Supplied as a GMP-grade material for use in pre-clinical and clinical studies.

Basic Information

Product Name	Eletriptan
CAS No.	143322-58-1
Molecular Formula	C22H26N2O2S
Molecular Weight	382.52 g/mol
Synonyms	Eletriptan (Base); UK-116,044; (R)-3-[(1-Methyl-2-pyrrolidinyl)methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole; Eletriptan Free Base; L-741,519; Relpax (Brand Name, refers to the HBr salt); UNII-4X2E6B3C8F
EINECS	Contact for details

Quality Control

Our Eletriptan is manufactured and tested under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical development and manufacturing. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality commitment ensures compliance with relevant guidelines for active pharmaceutical ingredients (APIs).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.