Description

4-(9,10-Didehydroergolin-8-Yl)Methylpiperazine-2,6-Dione is a complex heterocyclic compound belonging to the ergoline alkaloid class, serving as a critical advanced intermediate in pharmaceutical synthesis. Its value lies in its role as a key building block for developing novel therapeutic agents targeting neurological and cardiovascular systems. This high-purity intermediate is essential for research institutions and pharmaceutical manufacturers engaged in the development of innovative drugs, particularly within the neuropharmacology and receptor modulation fields.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of novel ergoline-based active pharmaceutical ingredients (APIs).
• Neurological Research: Used in the research and development of compounds targeting serotonin and dopamine receptor systems.
• Chemical Synthesis: Serves as a sophisticated building block for constructing complex polycyclic molecular architectures in medicinal chemistry.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Preclinical Studies: Utilized in the synthesis of candidate molecules for pharmacological evaluation and toxicology assessments.

Basic Information

Product Name	4-(9,10-Didehydroergolin-8-Yl)Methylpiperazine-2,6-Dione
CAS No.	131816-89-2
Molecular Formula	C21H23N3O2
Molecular Weight	349.43 g/mol
Synonyms	4-[(6aR,9R,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]methylpiperazine-2,6-dione; 4-(9,10-Didehydro-6-methyl-8β-ergolinyl)methyl-2,6-piperazinedione; Ergoline-8β-methanol, 9,10-didehydro-6-methyl-, 4-(2,6-dioxopiperazinyl)methyl deriv.; (8β)-9,10-Didehydro-6-methylergoline-8-methanol, 4-(2,6-dioxo-1-piperazinyl)methyl deriv.
EINECS	Contact for details

Quality Control

Our 4-(9,10-Didehydroergolin-8-Yl)Methylpiperazine-2,6-Dione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.