Description

Sumatriptan Succinate CAS NO 103628-48-4 is the succinate salt form of sumatriptan, a selective serotonin (5-HT1) receptor agonist. This active pharmaceutical ingredient (API) is critical for the effective treatment of acute migraine and cluster headache attacks. It is an essential raw material for pharmaceutical manufacturers producing generic and branded migraine medications in tablet, nasal spray, and injectable formulations.

Application

• Pharmaceutical API: Primary active ingredient in the formulation of anti-migraine drugs.
• Tablet Manufacturing: Used in the production of oral tablets for the acute treatment of migraine.
• Nasal Spray Formulations: Key component in fast-acting nasal spray products for rapid migraine relief.
• Injectable Solutions: Utilized in the preparation of subcutaneous injections for severe migraine and cluster headache episodes.
• Generic Drug Production: Serves as the core API for manufacturers developing bioequivalent generic versions of sumatriptan medications.
• Research & Development: Used in pharmacological studies and the development of new headache therapies.

Basic Information

Product Name	Sumatriptan Succinate
CAS No.	103628-48-4
Molecular Formula	C18H26N4O3S • C4H6O4
Molecular Weight	413.5 g/mol (for the succinate salt)
Synonyms	Sumatriptan Succinate; Sumatriptan Hemisuccinate; 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate; 1H-Indole-5-methanesulfonamide, 3-[2-(dimethylamino)ethyl]-N-methyl-, (1:1) salt with butanedioic acid; GR 43175X; Imigran (trade name); Imitrex (trade name); Migranal (related product).
EINECS	Contact for details

Quality Control

Our Sumatriptan Succinate is manufactured under strict quality management systems. It is produced to meet high-purity standards suitable for pharmaceutical use, with typical specifications aligning with major pharmacopoeial guidelines. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling. A Certificate of Analysis (COA) documenting purity, related substances, residual solvents, and other critical parameters is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this light-sensitive and moisture-sensitive compound.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.