Description

Frovatriptan CAS NO 147009-08-3 is a potent and selective serotonin (5-HT1B/1D) receptor agonist. This compound is a critical active pharmaceutical ingredient (API) valued for its efficacy in the acute treatment of migraine headaches. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of neurological therapeutics.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription migraine medications.
• Neurological Research: Used in preclinical and clinical studies investigating serotonin receptor pharmacology and migraine pathophysiology.
• Formulation Development: Serves as a key component in the R&D of various dosage forms, such as tablets and orally disintegrating tablets.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the commercial-scale production of finished drug products.
• Generic Drug Production: Essential for manufacturers producing bioequivalent generic versions of branded frovatriptan products.

Basic Information

Product Name	Frovatriptan
CAS No.	147009-08-3
Molecular Formula	C14H17N3O
Molecular Weight	243.31 g/mol
Synonyms	Frovatriptan Succinate (salt form); (R)-Frovatriptan; (3R)-3-(Methylamino)-1,2,3,4-tetrahydrocarbazole-6-carboxamide; 6-Carbamoyl-3-(methylamino)-1,2,3,4-tetrahydrocarbazole; SB-209509; FROVA (brand name); Migard; Almogran
EINECS	Contact for details

Quality Control

Our Frovatriptan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, impurity profiling, and residual solvent analysis, to ensure it meets high-purity standards suitable for pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.