Description

Sumatriptan CAS NO 103628-46-2 is a selective serotonin receptor agonist belonging to the triptan class of pharmaceuticals. This compound is critical for the effective treatment of acute migraine and cluster headache attacks, providing targeted relief by constricting blood vessels in the brain and blocking pain pathways. It is an essential active pharmaceutical ingredient (API) for pharmaceutical manufacturers developing generic and branded migraine medications in tablet, nasal spray, and injectable formulations.

Application

• Primary Active Pharmaceutical Ingredient (API) in oral tablets for migraine relief.
• Key component in nasal spray formulations for rapid-onset migraine treatment.
• Active agent in subcutaneous injection products for severe migraine and cluster headaches.
• Reference standard in analytical laboratories for quality control and method development.
• Raw material for research and development of new migraine therapeutics and drug delivery systems.
• Starting material for the synthesis of related triptan derivatives in pharmaceutical research.

Basic Information

Product Name	Sumatriptan
CAS No.	103628-46-2
Molecular Formula	C14H21N3O2S
Molecular Weight	295.40 g/mol
Synonyms	Sumatriptan Succinate; 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide; GR 43175; Imigran; Imitrex; Sumatran; Sumigra; Suminat; Sumatriptanum; Sumatriptano
EINECS	Contact for details

Quality Control

Our Sumatriptan is manufactured under strict quality management systems, ensuring it meets the rigorous standards required for pharmaceutical applications. Each batch is tested against comprehensive specifications, including identity, purity, and impurity profiles, with methods aligned to current pharmacopeial guidelines (e.g., USP, EP). A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 1.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm
Related Substances (HPLC)	Total impurities NMT 1.0% Any individual impurity NMT 0.5%
Microbial Enumeration	Meets USP <61> requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.