Description

(6Ar,9R,10Ar)-9-n-[3-(Dimethylamino)Propyl]-4-n-Ethyl-9-n-(Ethylcarbamoyl)-7-Prop-2-Enyl-6,6A,8,9,10,10A-Hexahydroindolo[4,3-Fg]Quinoline-4,9-Dicarboxamide is a complex, high-purity synthetic organic compound featuring a polycyclic indoloquinoline core. This molecule is of significant interest for its potential as a key intermediate or active pharmaceutical ingredient (API) in advanced research and development. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly within neurological or receptor-targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel drug candidates, especially those targeting complex biological pathways.
• Active Pharmaceutical Ingredient (API) Research: Used as a reference standard or as the core structure in the development of new APIs for preclinical and clinical studies.
• Medicinal Chemistry & Drug Discovery: Provides a sophisticated scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties.
• Biochemical Research: Employed as a tool compound in pharmacological assays to study receptor interactions, enzyme inhibition, or cellular signaling mechanisms.
• Fine Chemical Synthesis: Acts as a specialized intermediate for custom synthesis projects requiring complex heterocyclic frameworks.
• Reference Standard for Analytical Development: Used in HPLC, LC-MS, or NMR method development and validation for quality control in pharmaceutical manufacturing.

Basic Information

Product Name	(6Ar,9R,10Ar)-9-n-[3-(Dimethylamino)Propyl]-4-n-Ethyl-9-n-(Ethylcarbamoyl)-7-Prop-2-Enyl-6,6A,8,9,10,10A-Hexahydroindolo[4,3-Fg]Quinoline-4,9-Dicarboxamide
CAS No.	126554-50-5
Molecular Formula	C₃₃H₄₄N₆O₃
Molecular Weight	560.75 g/mol
Synonyms	9-N-[3-(Dimethylamino)propyl]-4-N-ethyl-9-N-(ethylcarbamoyl)-7-(prop-2-en-1-yl)-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-4,9-dicarboxamide; 126554-50-5; Indolo[4,3-fg]quinoline derivative; 7-Allyl-9-[3-(dimethylamino)propyl]-4-ethyl-9-(ethylcarbamoyl)-4,9-dicarboxamide hexahydroindoloquinoline; (6aR,9R,10aR)-isomer of the above compound.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet the specific requirements of your research or cGMP development phase.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage under an inert atmosphere is recommended to maintain stability. Keep container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.