Description

Zolmitriptan CAS NO 139264-17-8 is a potent and selective serotonin (5-HT1B/1D) receptor agonist. This compound is a critical active pharmaceutical ingredient (API) primarily used in the treatment of acute migraine headaches. It is essential for pharmaceutical manufacturers developing fast-acting and effective migraine therapies. The global demand for this API is driven by its proven efficacy in providing relief from migraine symptoms, including pain, nausea, and sensitivity to light and sound.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription migraine medications (tablets, orally disintegrating tablets, and nasal sprays).
• Generic Drug Formulation: Serves as the core component for manufacturers producing generic versions of branded zolmitriptan products.
• Clinical Research: Used in preclinical and clinical studies for developing new migraine treatments and combination therapies.
• Reference Standard: High-purity grades are utilized as analytical reference standards in quality control laboratories for method development and validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for finished dosage form production.

Basic Information

Product Name	Zolmitriptan
CAS No.	139264-17-8
Molecular Formula	C16H21N3O2
Molecular Weight	287.36 g/mol
Synonyms	Zolmitriptan; (S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone; 311C90; Zomig; Zolmitriptanum; Zolmitriptano; Zolmitriptanum [INN-Latin]; Zolmitriptan [USAN:INN]; UNII-2FS66TH3YW
EINECS	Contact for details

Quality Control

Our Zolmitriptan is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure it meets stringent pharmacopeial standards, including identification, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specifications for pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 1.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm
Related Substances (HPLC)	Total impurities: NMT 1.0% Any individual impurity: NMT 0.5%
Optical Rotation	Specific range provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.