Description

Dotarizine CAS NO 84625-59-2 is a high-purity pharmaceutical intermediate and research chemical belonging to the piperazine derivative class. This compound is of significant commercial interest for its role in the synthesis of advanced active pharmaceutical ingredients (APIs) and novel therapeutic agents. It is primarily sought by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors for development and production purposes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new therapeutic compounds, particularly in central nervous system (CNS) research.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce specific piperazine-based pharmacophores.
• Biochemical Research: Serves as a reference standard or reagent in biochemical assays and pharmacological studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Dotarizine
CAS No.	84625-59-2
Molecular Formula	C19H21FN2O2S
Molecular Weight	360.45 g/mol
Synonyms	1-(Diphenylmethyl)-4-(3-(2-thienylcarbonyl)propyl)piperazine; Dotarizina; Dotarizin; UNII-2X8Q1R7B4K; 2-Thiophenecarboxylic acid, 3-[4-(diphenylmethyl)-1-piperazinyl]propyl ester; 3-[4-(Diphenylmethyl)-1-piperazinyl]propyl 2-thiophenecarboxylate
EINECS	Contact for details

Quality Control

Our Dotarizine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.