Description

Ergotaminine Methanesulfonate is a high-purity ergot alkaloid derivative, specifically the methanesulfonate salt of ergotaminine. This compound is valued for its role as a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on neurological and cardiovascular therapeutics, as well as analytical laboratories requiring precise calibration materials.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the quality control and assay development of ergot-based APIs and finished drug products.
• Biochemical Research: Used in studies investigating the pharmacological activity, metabolism, and receptor binding profiles of ergot alkaloids.
• Analytical Chemistry: Employed as a critical component in method development and validation for HPLC, LC-MS, and other chromatographic techniques.
• Process Chemistry Intermediate: Acts as a key synthetic building block in the production of more complex ergot derivatives for clinical evaluation.

Basic Information

Product Name	Ergotaminine Methanesulfonate
CAS No.	74137-68-1
Molecular Formula	C34H37N5O6 • CH3SO3H
Molecular Weight	Contact for details
Synonyms	Ergotaminine Mesylate; Ergotaminine Methanesulphonate; 12'-Hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trione methanesulfonate; Ergotaminine monomethanesulfonate
EINECS	Contact for details

Quality Control

Our Ergotaminine Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.