Description

5'α-Benzyl-12'-Hydroxy-2'-Isopropylergotaman-3',6',18-Trione Phosphate is a specialized ergot alkaloid derivative, a class of compounds known for their complex molecular architecture and significant biological activity. This compound is valued in advanced pharmaceutical research and development for its potential as a key synthetic intermediate or a pharmacologically active scaffold. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in the fields of neurology and endocrinology. Our supply is characterized by high purity and batch-to-batch consistency, ensuring reliable results for critical applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of complex drug candidates, particularly those targeting neurological pathways.
• Biochemical Research: Used as a reference standard or experimental compound in studies investigating the mechanisms of action of ergot alkaloids and their derivatives.
• Medicinal Chemistry: Acts as a core scaffold for the design, synthesis, and structure-activity relationship (SAR) studies of new chemical entities with potential therapeutic value.
• Analytical Standard: Employed as a high-purity standard in analytical methods such as HPLC and LC-MS for the quantification and qualification of related substances in pharmaceutical products.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and process development.

Basic Information

Product Name	5'α-Benzyl-12'-Hydroxy-2'-Isopropylergotaman-3',6',18-Trione Phosphate
CAS No.	6424-36-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ergotaman-3',6',18-trione, 5'-(phenylmethyl)-12'-hydroxy-2'-(1-methylethyl)-, phosphate (1:1); 5'α-Benzyl-12'-hydroxy-2'-isopropylergotaman-3',6',18-trione phosphate; 2'-Isopropyl-5'α-benzyl-12'-hydroxyergotaman-3',6',18-trione phosphate; Benzylisopropylhydroxyergotamanetrione phosphate; Ergot alkaloid phosphate derivative; 6424-36-8; 5'-Benzyl-12'-hydroxy-2'-isopropylergotaman-3',6',18-trione phosphate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed using advanced chromatographic and spectroscopic techniques to confirm identity, purity, and the absence of critical impurities. We adhere to a strict quality management system, and Certificates of Analysis (COA) detailing specific test results are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.