Description

Pizotifen Malate CAS NO 5189-11-7 is a high-purity pharmaceutical active ingredient, specifically a serotonin antagonist. This compound is critical for the development and production of effective therapeutic formulations targeting specific neurological pathways. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development of migraine prophylaxis and related treatments.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of migraine prophylactic medications.
• Key intermediate in advanced pharmaceutical research and development for neurological disorders.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Biochemical research tool for studying serotonin (5-HT) receptor interactions and pharmacology.
• Formulation studies for developing various dosage forms such as tablets.

Basic Information

Product Name	Pizotifen Malate
CAS No.	5189-11-7
Molecular Formula	C19H21NS • C4H6O5
Molecular Weight	429.48 g/mol
Synonyms	Pizotyline Malate; BC-105 Malate; 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine Malate; 3-(1-Methyl-4-piperidylidene)-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one Malate; Pizotifen Hydrogen Malate; Mosegor; Sandomigran; Litec
EINECS	Contact for details

Quality Control

Our Pizotifen Malate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.