Description

Methysergide is a synthetic ergot alkaloid derivative known for its potent pharmacological activity. This compound is a critical intermediate and active pharmaceutical ingredient (API) in the research and development of therapeutic agents. It is primarily utilized by the pharmaceutical industry for the development and production of medications targeting specific neurological and vascular conditions. Our high-purity Methysergide CAS NO 361-37-5 ensures reliable performance and consistency for demanding industrial and research applications.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the manufacture of prescription medications.
• Critical research chemical in pharmacological studies and neuroscience research.
• Key intermediate in the synthesis of more complex ergot-derived pharmaceutical compounds.
• Development of therapeutic agents for the prophylaxis of severe migraine and cluster headaches.
• Investigational use in studying serotonin receptor antagonists and their mechanisms of action.
• Reference standard in analytical laboratories for quality control and method development.

Basic Information

Product Name	Methysergide
CAS No.	361-37-5
Molecular Formula	C₂₁H₂₇N₃O₂
Molecular Weight	353.46 g/mol
Synonyms	Methysergide Maleate (common salt); 1-Methyl-D-lysergic acid butanolamide; Deseril; Sansert; UML-491; 9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-1,6-dimethylergoline-8β-carboxamide; N-(1-Hydroxymethylpropyl)-1-methyl-D-lysergamide
EINECS	206-632-8

Quality Control

Our Methysergide is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.