Description

12'-Hydroxy-2',5'α-Diisopropylergotaman-3',6',18-Trione Methanesulphonate is a high-purity, semi-synthetic ergot alkaloid derivative, valued for its specific biological activity and structural complexity. This compound is critical for advanced pharmaceutical research and development, particularly in the study of neurological and vascular receptors. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and analytical reference standards.

Application

• Pharmaceutical Reference Standard: Serves as a certified analytical standard for quality control and method validation in drug development and manufacturing.
• Biochemical Research: Used as a key intermediate or tool compound in pharmacological studies targeting serotonin (5-HT) and dopamine receptor systems.
• Active Pharmaceutical Ingredient (API) Synthesis: Acts as a crucial precursor in the multi-step synthesis of specialized ergot-based pharmaceuticals.
• Academic Research: Employed in university and institutional labs for studying the structure-activity relationships (SAR) of complex alkaloids.
• Process Development: Used in scaling up and optimizing synthetic routes for the production of related therapeutic compounds.

Basic Information

Product Name	12'-Hydroxy-2',5'α-Diisopropylergotaman-3',6',18-Trione Methanesulphonate
CAS No.	2207-69-4
Molecular Formula	C35H45N5O7S
Molecular Weight	679.83 g/mol
Synonyms	Dihydroergocristine Methanesulfonate; 12'-Hydroxy-2',5'-α-diisopropylergotaman-3',6',18-trione Methanesulfonate; Dihydroergocristine Mesylate; 9,10-Dihydroergocristine Methanesulphonate; 2',5'-α-Diisopropyl-12'-hydroxyergotaman-3',6',18-trione Methanesulfonate; DHEC Mesylate; (5'α)-12'-Hydroxy-2',5'-diisopropylergotaman-3',6',18-trione Methanesulfonate
EINECS	Contact for details

Quality Control

Our 12'-Hydroxy-2',5'α-Diisopropylergotaman-3',6',18-Trione Methanesulphonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.