Description

Zolmitriptan Usp Rc C (Base) is a high-purity pharmaceutical intermediate and reference standard, identified by CAS No. 1346599-24-3. This compound is critical for ensuring the quality, efficacy, and consistency of finished drug products in the pharmaceutical manufacturing supply chain. It is primarily required by pharmaceutical companies, contract research organizations (CROs), and analytical laboratories engaged in the development, production, and quality control of migraine therapeutics.

Application

• Pharmaceutical Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key intermediate in the production of Zolmitriptan, a medication used for the acute treatment of migraine headaches.
• Reference Standard for Quality Control: Used as a certified reference material (CRM) in HPLC, GC, and other analytical methods to verify the identity, purity, and potency of drug substances and products.
• Research and Development (R&D): Employed in preclinical and clinical research for developing new formulations, generics, or studying the pharmacokinetics of triptan-class drugs.
• Regulatory Compliance and Documentation: Essential for generating data to support regulatory filings (e.g., ANDA, NDA) with agencies like the US FDA, ensuring compliance with pharmacopeial standards such as USP.
• Analytical Method Development and Validation: Acts as a benchmark compound for developing, optimizing, and validating new analytical testing procedures in quality control laboratories.

Basic Information

Item	Details
Product Name	Zolmitriptan Usp Rc C (Base)
CAS No.	1346599-24-3
Molecular Formula	C16H21N3O2
Molecular Weight	287.36 g/mol
Synonyms	Zolmitriptan Base; Zolmitriptan Free Base; (4S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1,3-oxazolidin-2-one; Zolmitriptan Impurity C; Zolmitriptan Related Compound C; Zolmitriptan USP RC C; UNII-2FS66TH3YW; Zomig Intermediate
EINECS	Contact for details

Quality Control

Every batch of Zolmitriptan Usp Rc C (Base) is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry and pharmacopeial standards, including USP monographs. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.