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Almotriptan CAS NO 181183-52-8
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CAS No.:181183-52-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Almotriptan is a selective serotonin (5-HT1B/1D) receptor agonist belonging to the triptan class of pharmaceuticals. This compound is a critical active pharmaceutical ingredient (API) specifically developed for the acute treatment of migraine headaches with or without aura. It is essential for pharmaceutical manufacturers and R&D organizations focused on neurology and central nervous system (CNS) therapeutics. The product is supplied as a high-purity material suitable for formulation development and commercial drug production.
Application
- Primary use as the Active Pharmaceutical Ingredient (API) in the manufacture of prescription migraine medications.
- Formulation into solid oral dosage forms such as tablets for the acute treatment of migraine attacks.
- Research and development of novel drug delivery systems for triptan-class therapeutics.
- Use as a reference standard in analytical laboratories for quality control and method development.
- Preclinical and clinical studies investigating serotonin receptor pharmacology.
- Production of generic versions of branded Almotriptan-based pharmaceuticals.
Basic Information
| Item | Details |
|---|---|
| Product Name | Almotriptan |
| CAS No. | 181183-52-8 |
| Molecular Formula | C17H25N3O2S |
| Molecular Weight | 335.47 g/mol |
| Synonyms | Almotriptan; 1-[[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]pyrrolidine; LAS 31416; Almogran; AXERT; Almotriptan Malate; UNII-4I86B4NQ5L |
| EINECS | Contact for details |
Quality Control
Our Almotriptan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide full traceability and support regulatory submissions with comprehensive documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material is light-sensitive and should be handled under appropriate conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to reference standard |
| Identification (HPLC) | Conforms to reference standard |
| Assay (HPLC) | ≥ 98.5% |
| Related Substances (HPLC) | Total impurities ≤ 1.0% Any single impurity ≤ 0.5% |
| Residual Solvents (GC) | Complies with ICH Q3C |
| Heavy Metals | ≤ 20 ppm |
| Loss on Drying | ≤ 0.5% |
| Sulfated Ash | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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