Description

Eletriptan Hydrobromide is a high-purity active pharmaceutical ingredient (API) and a selective serotonin (5-HT1B/1D) receptor agonist. It is a critical compound in the development and manufacturing of effective acute migraine treatments. This product is essential for pharmaceutical companies and research institutions engaged in the formulation of solid dosage forms, such as tablets, and in advanced neurological research. Eletriptan Hydrobromide CAS NO 177834-92-3 is supplied under stringent quality control to ensure reliability for commercial and developmental use.

Application

• Pharmaceutical API: Primary active ingredient in the commercial manufacture of prescription migraine medications.
• Formulation Development: Used in R&D for developing and optimizing solid oral dosage forms, including coated tablets.
• Reference Standard: Serves as a high-purity chemical reference standard for quality control and analytical method development in laboratories.
• Clinical Trial Materials: Sourced for the production of materials used in bioequivalence studies and clinical research.
• Neurological Research: Utilized in preclinical and pharmacological studies investigating serotonin receptor mechanisms.
• Generic Drug Manufacturing: Key starting material for companies producing generic versions of branded migraine therapeutics.

Basic Information

Product Name	Eletriptan Hydrobromide
CAS No.	177834-92-3
Molecular Formula	C22H27BrN2O2S
Molecular Weight	463.43 g/mol
Synonyms	(R)-3-[(1-Methyl-2-pyrrolidinyl)methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole hydrobromide; UK-116,044-046; Eletriptan HBr; Relpax (brand name API); 1H-Indole, 3-[(1-methyl-2-pyrrolidinyl)methyl]-5-[2-(phenylsulfonyl)ethyl]-, hydrobromide, (R)-; UNII-6XC1F6V8AI
EINECS	Contact for details

Quality Control

Our Eletriptan Hydrobromide is manufactured and tested to meet the exacting standards required for pharmaceutical intermediates and APIs. Quality is assured through a comprehensive battery of analytical tests including HPLC for assay and related substances, residual solvent analysis, and stringent control of elemental impurities. A Certificate of Analysis (COA) is provided with each batch, detailing compliance with agreed specifications. Our quality system supports development under GMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.