Description

Almotriptan is a potent and selective serotonin (5-HT1B/1D) receptor agonist. This compound is a critical active pharmaceutical ingredient (API) primarily used in the treatment of acute migraine headaches. It is essential for pharmaceutical manufacturers developing and producing effective migraine relief medications. The global demand for this high-purity intermediate is driven by the pharmaceutical and research sectors.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription migraine medications.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in laboratories.
• Research & Development: Used in preclinical and clinical studies to investigate new formulations or delivery mechanisms for triptan-class drugs.
• Generic Drug Manufacturing: A key starting material for the synthesis of generic versions of branded Almotriptan-based drugs.

Basic Information

Product Name	Almotriptan
CAS No.	154323-57-6
Molecular Formula	C17H25N3O2S
Molecular Weight	335.47 g/mol
Synonyms	Almotriptan; 1-[[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]pyrrolidine; LAS 31416; Almogran; AXERT; Eletriptan Impurity; 5-HT1B/1D Receptor Agonist
EINECS	Contact for details

Quality Control

Our Almotriptan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, consistent with ICH guidelines. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.