Description

Alniditan is a selective serotonin receptor agonist, specifically developed for research into the pathophysiology and treatment of migraine and other vascular headaches. Its high selectivity and well-defined pharmacological profile make it a valuable reference standard and active pharmaceutical ingredient (API) intermediate for advanced pharmaceutical development. This compound is essential for researchers in neuropharmacology and for manufacturers developing next-generation therapeutic agents targeting 5-HT1B/1D receptors.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Neuropharmacological Research: A critical tool for in vitro and in vivo studies investigating serotonin receptor (5-HT1B/1D) function, signal transduction, and ligand-receptor interactions.
• Migraine Research Compound: Employed in preclinical research to study the mechanisms of cranial vasoconstriction and the development of potential anti-migraine therapeutics.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key synthetic intermediate in the controlled production of specialized pharmaceutical formulations.
• Biochemical Assay Development: Utilized in high-throughput screening (HTS) assays and binding studies to identify and characterize new receptor modulators.

Basic Information

Product Name	Alniditan
CAS No.	152317-89-0
Molecular Formula	C19H24N4O3S
Molecular Weight	388.48 g/mol
Synonyms	3-[4-[4-(1,3-Benzodioxol-5-yl)-1-piperazinyl]butyl]-1,3-oxazolidin-2-one; LU-27860; LU 27860; Alniditan [INN]; 1,3-Benzodioxol-5-yl-piperazine Derivative LU-27860; 3-[4-[4-(1,3-Benzodioxol-5-yl)piperazin-1-yl]butyl]-1,3-oxazolidin-2-one
EINECS	Contact for details

Quality Control

Our Alniditan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation (IR, MS) to ensure it meets stringent research-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic and should be handled under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.