Description

Pranidipine is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) belonging to the dihydropyridine class of calcium channel blockers. It serves as a critical building block in the research and development of novel cardiovascular therapeutics targeting hypertension and angina. This compound is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions engaged in drug discovery and synthesis. We supply Pranidipine CAS NO 99522-79-9 to the global market with a focus on consistent quality and reliable supply chain integrity.

Application

• Pharmaceutical API Synthesis: Primary use as an active pharmaceutical ingredient in the formulation of calcium channel blocker medications.
• Cardiovascular Drug Research: Key intermediate in the discovery and development of new antihypertensive and antianginal drugs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical testing laboratories.
• Biochemical Research: Used in pharmacological studies to investigate calcium channel mechanisms and vascular smooth muscle function.
• Process Development: Employed in scaling up and optimizing synthetic routes for commercial pharmaceutical production.
• Custom Synthesis: Starting material for the preparation of novel dihydropyridine derivatives and analogs in medicinal chemistry.

Basic Information

Product Name	Pranidipine
CAS No.	99522-79-9
Molecular Formula	C₂₇H₃₃N₃O₆
Molecular Weight	495.57 g/mol
Synonyms	Pranidipine; (±)-Pranidipine; CS-905; 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[2-[N-benzyl-N-(phenylmethyl)amino]ethyl] 5-methyl ester; 3-[2-(Dibenzylamino)ethyl] 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
EINECS	Contact for details

Quality Control

Our Pranidipine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. Our quality commitment aligns with cGMP principles to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.