Description

Diethyl 4-(4-Hydroxyphenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate is a high-purity, functionalized 1,4-dihydropyridine (DHP) derivative, a core structural motif in medicinal chemistry. This compound matters as a versatile and critical pharmaceutical intermediate for the synthesis of advanced drug candidates, particularly those targeting cardiovascular and neurological pathways. It is essential for R&D chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require reliable, high-quality building blocks for complex molecule synthesis.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a precursor for the development of calcium channel blockers and other bioactive molecules with the 1,4-dihydropyridine core.
• Research & Development (R&D): Used in academic and industrial laboratories for structure-activity relationship (SAR) studies and the discovery of new therapeutic agents.
• Agrochemical Intermediate: Potential application in the synthesis of novel pesticides and herbicides due to its bioactive heterocyclic structure.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	Diethyl 4-(4-Hydroxyphenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate
CAS No.	10354-30-0
Molecular Formula	C19H23NO5
Molecular Weight	345.39 g/mol
Synonyms	4-(4-Hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester; Diethyl 1,4-dihydro-2,6-dimethyl-4-(4-hydroxyphenyl)-3,5-pyridinedicarboxylate; Hantzsch Ester Derivative; 1,4-DHP Derivative; 4-Hydroxy Hantzsch Ester; 4-Aryl-1,4-dihydropyridine; DEHP; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Diethyl 4-(4-Hydroxyphenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications and test results (e.g., HPLC purity, NMR confirmation) is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.