Description

Lercanidipinehcl CAS NO 100427-27-8 is the hydrochloride salt of lercanidipine, a third-generation dihydropyridine calcium channel blocker. This high-purity active pharmaceutical ingredient (API) is critical for the development and manufacturing of antihypertensive medications. It is primarily required by pharmaceutical companies and research institutions engaged in cardiovascular drug formulation and advanced pharmacological studies.

Application

• Pharmaceutical API: Core active ingredient in the formulation of antihypertensive drugs for the treatment of hypertension.
• Finished Dosage Forms: Used in the production of oral solid dosage forms, primarily tablets.
• Research & Development: Serves as a reference standard and key intermediate in preclinical and clinical research for cardiovascular diseases.
• Generic Drug Manufacturing: Essential for companies developing bioequivalent generic versions of branded lercanidipine medications.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for pharmaceutical production.
• Analytical Testing: Used as a certified reference material in quality control laboratories for HPLC and other analytical methods.

Basic Information

Product Name	Lercanidipine Hydrochloride
CAS No.	100427-27-8
Molecular Formula	C36H41N3O6 • HCl
Molecular Weight	648.19 g/mol
Synonyms	Lercanidipine HCl; Lercanidipine Hydrochloride; (2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride); Lercanidipine Monohydrochloride; Lercadip; Zanidip; Lercanidipinum Hydrochloridum; Lercanidipine (Hydrochloride)
EINECS	Contact for details

Quality Control

Our Lercanidipine Hydrochloride is manufactured under strict quality management systems. We provide material that meets or exceeds relevant pharmacopeial standards, including in-process controls and final release testing. A comprehensive Certificate of Analysis (COA) is supplied with each batch, detailing purity, identity, and impurity profiles to ensure compliance with your specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.