Description

Fendiline is a synthetic organic compound belonging to the class of calcium channel blockers, specifically a non-selective calmodulin antagonist. This compound is of significant interest in pharmaceutical research and development for its potential therapeutic effects. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of cardiovascular and neurological agents. The material is supplied as a high-purity chemical for advanced research applications.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis and study of novel calcium channel blockers and calmodulin inhibitors.
• Cardiovascular Drug Discovery: Used in preclinical studies to investigate mechanisms for managing conditions like angina pectoris and hypertension due to its vasodilatory properties.
• Neurological Research: Employed in biochemical assays to study the role of calmodulin and calcium signaling in neurological pathways and potential treatments for related disorders.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Tool Compound: Utilized in cell-based and in vitro studies to modulate intracellular calcium levels and study associated cellular processes.

Basic Information

Product Name	Fendiline
CAS No.	13042-18-7
Molecular Formula	C23H23N
Molecular Weight	313.44 g/mol
Synonyms	Fendiline; (±)-Fendiline; Fendiline Hydrochloride (salt form); 1,1-Diphenyl-3-piperidinopropane; 3-(N-Piperidino)-1,1-diphenylpropane; 3-(1-Piperidinyl)-1,1-diphenyl-1-propane; P-252; Phenoxene; Sensitol
EINECS	235-915-8

Quality Control

Our Fendiline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and GC. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for materials intended for pharmaceutical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.