Description

Methoxyverapamil Hydrochloride CAS NO 16662-47-8 is a high-purity pharmaceutical intermediate and research chemical, primarily known as a calcium channel blocker analog. It is critical for the development and synthesis of advanced cardiovascular research compounds and active pharmaceutical ingredients (APIs). This product is essential for pharmaceutical R&D laboratories, academic research institutions, and manufacturers specializing in cardiovascular and neurological therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced calcium channel blocker drugs and related analogs.
• Biochemical Research: Used as a reference standard and tool compound in cardiovascular and neuropharmacology studies.
• API Development: Serves as a precursor in the development and scale-up of new Active Pharmaceutical Ingredients (APIs).
• Mechanistic Studies: Employed in vitro and in vivo to investigate calcium channel function and vascular smooth muscle physiology.
• Academic Research: Utilized in university and institutional labs for pharmacological and medicinal chemistry projects.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Methoxyverapamil Hydrochloride
CAS No.	16662-47-8
Molecular Formula	C27H39ClN2O5
Molecular Weight	507.06 g/mol
Synonyms	Methoxyverapamil HCl; D-600; Gallopamil Hydrochloride (Note: Gallopamil is a very closely related derivative); (2-Isopropyl-5-methoxyphenethyl)methylamino]-3,4-dimethoxyphenylacetonitrile Hydrochloride; α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)benzenecetonitrile Hydrochloride; Verapamil Derivative; (±)-Methoxyverapamil Hydrochloride
EINECS	Contact for details

Quality Control

Our Methoxyverapamil Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.