Description

Nimodipine CAS NO 66085-59-4 is a high-purity dihydropyridine calcium channel blocker specifically designed for pharmaceutical research and development. This compound is critical for its selective action on cerebral blood vessels, making it a key intermediate and active pharmaceutical ingredient (API) in neurological therapeutics. It is primarily utilized by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers serving the global healthcare sector.

Application

• Pharmaceutical API: Primary use as the active ingredient in formulations for the treatment and prevention of cerebral vasospasm following subarachnoid hemorrhage.
• Neurological Research: Critical reagent in preclinical and clinical studies investigating cerebrovascular disorders and neuroprotection.
• Drug Development: Serves as a reference standard and building block in the synthesis of novel calcium channel modulators.
• Generic Drug Manufacturing: Essential for the production of generic nimodipine tablets, capsules, and injectable solutions.
• Analytical Standard: Used as a certified reference material (CRM) for quality control and assay validation in pharmaceutical analysis.

Basic Information

Product Name	Nimodipine
CAS No.	66085-59-4
Molecular Formula	C21H26N2O7
Molecular Weight	418.44 g/mol
Synonyms	Nimodipine; 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl 1-methylethyl ester; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-methoxyethyl 1-methylethyl ester; Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate; Bay e 9736; BAY-e-9736; Nimotop; Admon
EINECS	266-102-1

Quality Control

Our Nimodipine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with pharmaceutical-grade standards. Certificates of Analysis (COA) detailing all specifications are provided to guarantee traceability and supply chain reliability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature of 15-25°C (59-77°F) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.