Description

Methoxyverapamil Hydrochloride CAS NO 16662-46-7 is a high-purity pharmaceutical intermediate and research chemical, primarily known as a calcium channel blocker analog. This compound is critical for advanced pharmacological research and development, particularly in the study of cardiovascular mechanisms and drug discovery. It is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions focused on developing new therapeutic agents or studying cellular ion channel functions.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced calcium channel blocker drugs and related analogs.
• Biochemical Research: Used as a reference standard and active agent in cardiovascular and electrophysiology studies.
• Drug Discovery & Development: Serves as a crucial compound for screening and developing new therapeutic candidates targeting L-type calcium channels.
• Academic Research: Employed in university and institutional labs for pharmacological experiments and mechanism-of-action studies.
• Metabolism Studies: Utilized in ADME (Absorption, Distribution, Metabolism, and Excretion) research to understand drug interactions and pathways.
• Analytical Standard: Provides a high-purity reference material for quality control and method validation in analytical laboratories.

Basic Information

Product Name	Methoxyverapamil Hydrochloride
CAS No.	16662-46-7
Molecular Formula	C27H39ClN2O5
Molecular Weight	507.06 g/mol
Synonyms	D-600; Gallopamil Hydrochloride; Methoxyverapamil HCl; (2-Isopropyl-5-methoxyphenethyl)methylamino-2-(3,4,5-trimethoxyphenyl)-2-isopropylvaleronitrile Hydrochloride; (±)-Gallopamil Hydrochloride; α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4,5-trimethoxy-α-(1-methylethyl)benzenecetonitrile Hydrochloride; D600
EINECS	Contact for details

Quality Control

Our Methoxyverapamil Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with client specifications and relevant industry standards for research and pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.